王晨晖

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王晨晖

Title:副教授/博导

E-mail Address:wangchenhui@cqu.edu.cn

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个人/团队介绍

王晨晖,博士/副教授/博士生导师,bat365在线登录网站公司党委委员,经理助理,药理药剂系副主任。2007-2016年本硕博毕业于吉林董事长命科学学院,毕业后任职于bat365。目前主要从事蛋白药物递送载体设计,缓控释制剂以及肺部递药研究。目前以第一作者或通讯作者在国际主流药剂学期刊Journal of Controlled ReleaseACS Applied Materials & InterfacesInternational Journal of PharmaceuticsInternational Journal of Nanomedicine等杂志发表SCI论文15篇,主持国家自然科学基金青年项目、重庆市技术创新与应用发展专项重点项目等课题5项,作为副主编出版教材1部,承担省部级教改项目1项。荣获教育部高等学校药学类专业微课比赛特等奖,bat365在线登录网站第七届教学比赛一等奖,教育部高等学校药学类专业教学比赛二等奖,重庆市高校教师教学创新大赛三等奖。目前担任重庆市药理学会理事,重庆市科技青年联合会委员,bat365在线登录网站招生委员会委员。

学习工作经历

2007.9—2011.6  吉林大学     生物技术/工商管理          双学士学位

2011.9—2016.6  吉林大学  微生物与生化药学(药剂方向)    博士学位

2016.7—2018.9  bat365在线登录网站          bat365                讲师/硕导

2018.9—至今    bat365在线登录网站          bat365                副教授/博导

研究领域

药物传递新技术,蛋白药物递送载体设计,缓控释制剂,肺部递药研究

项目成果

1.重庆市技术创新与应用发展专项重点项目《预防和控制痴呆用的国家二类新药——S-奥拉西坦的研制》子课题,项目编号cstc2019jscx-gksbX0050,研究经费25万,主持人

2.家蚕基因组生物学国家重点实验室开放课题,项目编号SKLSGB-orp202010,研究经费10万,主持人

3.bat365在线登录网站学科交叉与团队建设专项,项目编号2020CDJQY-A041,研究经费15万,主持人

4.国家自然科学基金青年项目《ATP/pH双级响应多孔微球用于耐药肺癌的化药/基因联合治疗研究》,81703424,研究经费20.1万元,主持人

5.国家自然科学基金青年项目《天然产物aetheramide A的抗肿瘤构效关系和作用靶点确证》,项目编号21807009,研究经费24万元,参与人

6.中央高校基本科研业务费《吸入式载阿霉素微球治疗耐药肺癌的研究》,研究经费5万元,主持人

代表性文章

[1] Yang, Xiaohong; Xie, Beibei; Peng, Haibo; Shi, Gongming; Sreenivas, Banne; Guo, Jian; Wang, Chenhui*; He, Yun*, Eradicating intracellular MRSA via targeted delivery of lysostaphin and vancomycin with mannose-modified exosomes Journal of controlled release 2021 329:454-467

 

[2] Wenxi Li, Shuang Chen, Lanfang Zhang, Yan Zhang, Xiaohong Yang, Beibei Xie, Jian Guo, Yun He* and Chenhui Wang*, Inhalable functional mixed-polymer microspheres to enhance doxorubicin release behavior for lung cancer treatment [J], Colloids and surfaces. B-Biointerfaces, 2020, 196, 111350

 

[3] Xiaohong Yang, Gongming Shi, Jian Guo, Chenhui Wang* and Yun He*, Exosome-encapsulated antibiotic against intracellular infections of methicillin-resistant Staphylococcus aureus[J], International Journal of Nanomedicine, 2018, 29, 13: 8095-8104

 

[4] You, HengyaoVegi, Srinivas RaoLagishetti, ChandraiahChen, ShuoReddy, Rekula SanthoshYang, XiaohongGuo, JianWang, Chenhui*He, Yun*. Synthesis of Bioactive 3,4-Dihydro-2 H-naphtho[2,3- b][1,4]oxazine-5,10- dione and 2,3,4,5-Tetrahydro-1 H-naphtho[2,3- b]azepine-6,11-dione Derivatives via the Copper-Catalyzed Intramolecular Coupling Reaction.[J]. Journal of Organic Chemistry, 2018,83 (7): 4119-4130.

 

[5] Tingting Wang, Yaqin Tang, Xiao He, Ju Yan, Chenhui Wang* and Xuli Feng*, Self-Assembled Raspberry-Like Core/Satellite Nanoparticles for Anti-Inflammatory Protein Delivery [J]., ACS Appl. Mater. Interfaces, 2017, 9, 8: 6902–6907

 

[6] Wang Chenhui, Yang Jiebing, Han Haobo, Chen Jiawen, Wang Yudi, Li Quanshun*, Wang Yanbo*, Disulfiram-loaded porous PLGA microparticle for inhibiting the proliferation and migration of non-small-cell lung cancer[J]. International Journal of Nanomedicine, 2017, 12:827-837.

 

[7] Wang Chenhui, Yu Changhui, Yu Kongtong, Teng Lesheng, Liu Jiaxin, Wang Xuesong, Sun Fengying* and Li Youxin*, Improving Protein Stability and Controlling Protein Release by Adding Poly (Cyclohexane -1, 4 -Diyl Acetone Dimethylene Ketal) to PLGA Microspheres[J]., Curr Drug Deliv, 2016, 12(6): 726-735

 

[8] Chenhui Wang, Di Wu, Jiebing Yang, Haobo Han, Zhen Xing, Yan Zhang, Yan Yang* and Quanshun Li*, Porous PLGA microparticles to encapsulate doxorubicin and polyethylenimine/miR-34a for inhibiting the proliferation and migration of lung cancer[J]. Rsc Advances, 2015, 5(99):81445-81448.

 

[9] Chenhui Wang, Changhui Yu, Jiaxin Liu, Lesheng Teng, Fengying Sun* and Youxin Li*, Preparation and in vivo evaluation of PCADK/PLGA microspheres for improving stability and efficacy of rhGH[J], International journal of pharmaceutics, 2015, 495(2): 924-931.

 

[10] Chenhui Wang, Changhui Yu, Jiaxin Liu, Fengying Sun, Lesheng Teng* and Youxin Li*, Stabilization of Human Immunoglobulin G Encapsulated within Biodegradable Poly (Cyclohexane-1, 4-diyl Acetone Dimethylene Ketal) (PCADK)/ Poly (Lactic-co-Glycolic Acid) (PLGA) Blend Microspheres [J], Protein & Peptide Letters, 2015, 22, 11:963-971.